This book is a must for every synthetic chemist. With didactic
skill and clarity, K. C. Nicolaou and E. Sorensen present the most
remarkable and ingenious total syntheses from outstanding synthetic
organic chemists.
To make the complex strategies more accessible, especially to the
novice, each total synthesis is analyzed retrosynthetically. The
authors then carefully explain each synthetic step and give hints
on alternative methods and potential pitfalls. Numerous references
to useful reviews and the original literature make this book an
indispensable source of further information.
Special emphasis is placed on the skillful use of graphics and
schemes: Retrosynthetic analyses, reaction sequences, and
stereochemically crucial steps are presented in boxed sections
within the text. For easy reference, key intermediates are also
shown in the margins.
Graduate students and researchers alike will find this book a
gold mine of useful information essential for their daily work.
Every synthetic organic chemist will want to have a copy on his or
her desk.